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Non-stop decay
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Non-stop decay : ウィキペディア英語版
Non-stop decay
Non-stop decay is a cellular mechanism of mRNA surveillance to detect mRNA molecules lacking a stop codon and prevent these mRNAs from translation. The non-stop decay pathway releases ribosomes that have reached the far 3' end of an mRNA and guides the mRNA to the exosome complex for selective degradation by RNase R in bacteria. In contrast to NMD, polypeptides do not release from the ribosome, and thus, NSD seems to involve mRNA decay factors distinct from NMD.
== See also ==

* Nonsense mediated decay, another mRNA surveillance mechanism
* mRNA surveillance

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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